KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MSH6
All Species:
21.21
Human Site:
T633
Identified Species:
33.33
UniProt:
P52701
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52701
NP_000170.1
1360
152786
T633
Q
F
W
D
A
S
K
T
L
R
T
L
L
E
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001113749
1360
152750
T633
Q
F
W
D
A
S
K
T
L
R
T
L
L
E
E
Dog
Lupus familis
XP_531814
1283
145094
G607
E
L
A
L
S
A
L
G
G
C
V
F
Y
L
K
Cat
Felis silvestris
Mouse
Mus musculus
P54276
1358
151058
T632
Q
F
W
D
A
T
K
T
L
R
T
L
L
E
G
Rat
Rattus norvegicus
XP_002726765
1361
151628
T635
Q
F
W
D
A
T
K
T
L
R
T
L
L
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_419359
1466
164165
T739
Q
F
W
S
A
S
K
T
L
K
V
L
L
E
E
Frog
Xenopus laevis
NP_001089247
1340
149481
T612
Q
F
W
D
A
S
R
T
L
K
T
L
A
E
E
Zebra Danio
Brachydanio rerio
NP_878280
1369
153213
K632
S
Q
F
W
D
A
Q
K
T
L
K
V
L
A
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUM0
1190
133117
A528
P
N
D
N
Y
K
L
A
L
K
A
L
G
Q
C
Honey Bee
Apis mellifera
XP_392346
1120
127429
K458
L
H
E
G
D
Y
F
K
K
S
D
S
E
F
Q
Nematode Worm
Caenorhab. elegans
NP_491163
1186
133609
A524
D
W
Q
L
A
L
S
A
F
G
A
I
F
W
Y
Sea Urchin
Strong. purpuratus
XP_797647
1335
149141
G605
C
I
V
E
T
S
I
G
K
F
Y
I
G
Q
F
Poplar Tree
Populus trichocarpa
XP_002320307
1288
142120
L614
A
F
L
D
E
T
L
L
R
F
A
K
F
E
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04716
1324
146779
E606
D
S
E
K
T
I
Y
E
V
G
I
I
Y
K
R
Baker's Yeast
Sacchar. cerevisiae
Q03834
1242
140062
F580
K
K
V
G
F
S
A
F
G
G
L
L
Y
Y
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.3
88.1
N.A.
85.8
86.4
N.A.
N.A.
64.2
66.5
60
N.A.
39
41.2
34.4
48.6
Protein Similarity:
100
N.A.
98.6
91.3
N.A.
92.1
92.8
N.A.
N.A.
75.4
79.9
74.9
N.A.
57.6
58
52.7
66.6
P-Site Identity:
100
N.A.
100
0
N.A.
86.6
86.6
N.A.
N.A.
80
80
13.3
N.A.
13.3
0
6.6
6.6
P-Site Similarity:
100
N.A.
100
26.6
N.A.
93.3
93.3
N.A.
N.A.
86.6
93.3
40
N.A.
33.3
6.6
20
26.6
Percent
Protein Identity:
36.1
N.A.
N.A.
33.2
29
N.A.
Protein Similarity:
52
N.A.
N.A.
51.4
49.1
N.A.
P-Site Identity:
20
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
0
47
14
7
14
0
0
20
0
7
7
0
% A
% Cys:
7
0
0
0
0
0
0
0
0
7
0
0
0
0
7
% C
% Asp:
14
0
7
40
14
0
0
0
0
0
7
0
0
0
0
% D
% Glu:
7
0
14
7
7
0
0
7
0
0
0
0
7
47
34
% E
% Phe:
0
47
7
0
7
0
7
7
7
14
0
7
14
7
7
% F
% Gly:
0
0
0
14
0
0
0
14
14
20
0
0
14
0
14
% G
% His:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
0
0
0
7
7
0
0
0
7
20
0
0
0
% I
% Lys:
7
7
0
7
0
7
34
14
14
20
7
7
0
7
7
% K
% Leu:
7
7
7
14
0
7
20
7
47
7
7
54
40
7
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
0
7
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
40
7
7
0
0
0
7
0
0
0
0
0
0
14
7
% Q
% Arg:
0
0
0
0
0
0
7
0
7
27
0
0
0
0
7
% R
% Ser:
7
7
0
7
7
40
7
0
0
7
0
7
0
0
7
% S
% Thr:
0
0
0
0
14
20
0
40
7
0
34
0
0
0
0
% T
% Val:
0
0
14
0
0
0
0
0
7
0
14
7
0
0
0
% V
% Trp:
0
7
40
7
0
0
0
0
0
0
0
0
0
7
0
% W
% Tyr:
0
0
0
0
7
7
7
0
0
0
7
0
20
7
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _